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Inhibition of PP2A by LIS1 increases HIV-1 gene expression

BACKGROUND: Lissencephaly is a severe brain malformation in part caused by mutations in the LIS1 gene. LIS1 interacts with microtubule-associated proteins, and enhances transport of microtubule fragments. Previously we showed that LIS1 interacts with HIV-1 Tat protein and that this interaction was m...

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書目詳細資料
Main Authors: Epie, Nicolas, Ammosova, Tatyana, Turner, Willie, Nekhai, Sergei
格式: Artigo
語言:Inglês
出版: BioMed Central 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615876/
https://ncbi.nlm.nih.gov/pubmed/17018134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-3-65
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