Inhibition of Proprotein Convertases Enhances Cell Migration and Metastases Development of Human Colon Carcinoma Cells in a Rat Model

Although proprotein convertases are involved in tumor development, nothing is known about their role in metastatic dissemination. To investigate the involvement of convertase inhibition, we used human colon carcinoma cells overexpressing α1-antitrypsin Portland (α1-PDX, PDX39P cells), a potent conve...

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Detalhes bibliográficos
Main Authors: Nejjari, Mimoun, Berthet, Virginie, Rigot, Véronique, Laforest, Sullivan, Jacquier, Marie-France, Seidah, Nabil G., Remy, Lionel, Bruyneel, Erik, Scoazec, Jean-Yves, Marvaldi, Jacques, Luis, José
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615749/
https://ncbi.nlm.nih.gov/pubmed/15161629
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