Colorectal Pretumor Progression Before and After Loss of DNA Mismatch Repair

A pretumor progression model predicts many oncogenic cancer mutations may first accumulate in normal appearing colon. Although direct observations of early pretumor mutations are impractical, it may be possible to retrospectively reconstruct tumor histories from contemporary cancer mutations. To inf...

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Detalhes bibliográficos
Main Authors: Calabrese, Peter, Tsao, Jen-Lan, Yatabe, Yasushi, Salovaara, Reijo, Mecklin, Jukka-Pekka, Järvinen, Heikki J., Aaltonen, Lauri A., Tavaré, Simon, Shibata, Darryl
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615342/
https://ncbi.nlm.nih.gov/pubmed/15039232
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