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Design and Synthesis of Novel Hydrazide-Linked Bifunctional Peptides as δ/μ Opioid Receptor Agonists and CCK-1/CCK-2 Receptor Antagonists

A series of hydrazide-linked bifunctional peptides designed to act as agonists for δ /μ opioid receptors and antagonists for CCK-1/CCK-2 receptors was prepared and tested for binding to both opioid and CCK receptors and in functional assays. SAR studies in the CCK region examined the structural requ...

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Bibliografske podrobnosti
Main Authors: Lee, Yeon Sun, Agnes, Richard S., Badghisi, Hamid, Davis, Peg, Ma, Shou-wu, Lai, Josephine, Porreca, Frank, Hruby, Victor J.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1614704/
https://ncbi.nlm.nih.gov/pubmed/16509592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm05085
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