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AIP1: a new player in TNF signaling
Apoptosis signal–regulating kinase 1 (ASK1) is an upstream activator of JNK and p38 MAPK signaling cascades. Evidence now shows that the ASK1-interacting protein, AIP1, plays an important role in TNF-α–induced ASK1 activation by facilitating dissociation from its inhibitor.
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC161430/ https://ncbi.nlm.nih.gov/pubmed/12813014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318911 |
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