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AIP1: a new player in TNF signaling

Apoptosis signal–regulating kinase 1 (ASK1) is an upstream activator of JNK and p38 MAPK signaling cascades. Evidence now shows that the ASK1-interacting protein, AIP1, plays an important role in TNF-α–induced ASK1 activation by facilitating dissociation from its inhibitor.

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Detalhes bibliográficos
Main Authors: Guicciardi, M. Eugenia, Gores, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC161430/
https://ncbi.nlm.nih.gov/pubmed/12813014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318911
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