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Altered cutaneous immune parameters in transgenic mice overexpressing viral IL-10 in the epidermis

IL-10 is a pleiotropic cytokine that inhibits several immune parameters, including Th1 cell–mediated immune responses, antigen presentation, and antigen-specific T cell proliferation. Recent data implicate IL-10 as a mediator of suppression of cell-mediated immunity induced by exposure to UVB radiat...

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Detalhes bibliográficos
Main Authors: Ding, Wanhong, Beissert, Stefan, Deng, Liang, Miranda, Edward, Cassetty, Christopher, Seiffert, Kristina, Campton, Kristina L., Yan, Zhengmin, Murphy, George F., Bluestone, Jeffrey A., Granstein, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC161417/
https://ncbi.nlm.nih.gov/pubmed/12813028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315722
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