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Maribavir Antagonizes the Antiviral Action of Ganciclovir on Human Cytomegalovirus

The cytomegalovirus (CMV) UL97 kinase inhibitor maribavir antagonized the anti-CMV effect of ganciclovir, increasing the ganciclovir 50% inhibitory concentration against a sensitive strain by up to 13-fold. Antiviral activities of foscarnet and cidofovir were unaffected by maribavir.

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Autori principali: Chou, Sunwen, Marousek, Gail I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610080/
https://ncbi.nlm.nih.gov/pubmed/17005835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00577-06
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