Polymorphism of carbon oxidation of drugs and clinical implications.

Eight volunteers previously phenotyped for their ability to hydroxylate debrisoquine (four extensive metabolisers (EM), four poor metabolisers (PM) were investigated for their metabolic handling of guanoxan and phenacetin. All three drugs are oxidised at carbon centres. Oxidative dealkylation of phe...

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Bibliografiska uppgifter
Huvudupphovsmän: Sloan, T P, Mahgoub, A, Lancaster, R, Idle, J R, Smith, R L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1978
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1607381/
https://ncbi.nlm.nih.gov/pubmed/151576
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