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Genetically determined oxidation capacity and the disposition of debrisoquine.

1 The disposition in urine of debrisoquine and its hydroxylated metabolites has been studied in subjects of the 'extensive metabolizer' (EM; n = 5) and 'poor metabolizer' (PM; n = 5) phenotypes. The 4-hydroxylation of debrisoquine by PM subjects following a 10 mg oral dose was ca...

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Detaylı Bibliyografya
Asıl Yazarlar: Sloan, T P, Lancaster, R, Shah, R R, Idle, J R, Smith, R L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1983
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1427798/
https://ncbi.nlm.nih.gov/pubmed/6849780
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