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A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

A population survey of 258 unrelated white British subjects showed a polymorphism for the 4-oxidation of debrisoquine. "Extensive metabolisers" (EM) and "poor metabolisers" (PM) are recognisable, 8.9% of the population being PM. Nine pedigrees ascertained through PM probands show...

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Detalhes bibliográficos
Main Authors: Evans, D A, Mahgoub, A, Sloan, T P, Idle, J R, Smith, R L
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1048511/
https://ncbi.nlm.nih.gov/pubmed/7381862
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