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The herpes simplex virus thymidine kinase gene as a conditional negative-selection marker gene in Arabidopsis thaliana.

The human herpes simplex virus thymidine kinase type 1 gene (HSVtk) acts as a conditional lethal marker in mammalian cells. The HSVtk-encoded enzyme is able to phosphorylate certain nucleoside analogs (e.g. ganciclovir, an antiherpetic drug), thus converting them to toxic DNA replication inhibitors....

詳細記述

保存先:
書誌詳細
主要な著者: Czakó, M, Márton, L
フォーマット: Artigo
言語:Inglês
出版事項: 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC160706/
https://ncbi.nlm.nih.gov/pubmed/8165243
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