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Mortalin-Based Cytoplasmic Sequestration of p53 in a Nonmammalian Cancer Model
In nature the soft shell clam Mya arenaria develops a fatal neoplasm that shares molecular similarity with an unrelated group of human cancers. In leukemic clam hemocytes, wild-type p53 and mortalin proteins co-localize in the cytoplasm. A similar phenotype, characterized by cytoplasmic sequestratio...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1606587/ https://ncbi.nlm.nih.gov/pubmed/16651619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050603 |
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