Pathogenic Role of B Cells in Anti-CD40-Induced Necroinflammatory Liver Disease

Activated B cells function in antibody production and antigen presentation, but whether they perform any pathophysiological functions at sites of inflammation is not fully understood. Here, we report that intravenous injection of an agonistic anti-CD40 monoclonal antibody (αCD40) causes a biphasic i...

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Detalhes bibliográficos
Main Authors: Kimura, Kiminori, Moriwaki, Hisataka, Nagaki, Masahito, Saio, Masanao, Nakamoto, Yasunari, Naito, Makoto, Kuwata, Kazuo, Chisari, Francis V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606511/
https://ncbi.nlm.nih.gov/pubmed/16507894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050314
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