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Blockade of Neutrophil Elastase Attenuates Severe Liver Injury in Hepatitis B Transgenic Mice

Serine proteinases produced by polymorphonuclear neutrophils play important roles in neutrophil-mediated tissue injury at inflammatory sites. Although neutrophil recruitment to the liver has been shown to be involved in the exacerbation of liver inflammation, the function of neutrophil elastase (NE)...

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Detalhes bibliográficos
Main Authors: Takai, Shinji, Kimura, Kiminori, Nagaki, Masahito, Satake, Shinichi, Kakimi, Kazuhiro, Moriwaki, Hisataka
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315990/
https://ncbi.nlm.nih.gov/pubmed/16306586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15142-15150.2005
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