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Override of the Osteoclast Defect in Osteopontin-Deficient Mice by Metastatic Tumor Growth in the Bone

Osteopontin (OPN) is a major noncollagenous protein of bone that is frequently up-regulated in tumors, where it enhances tumor growth. OPN-deficient mice are resistant to stimulated bone resorption, including that occurring after ovariectomy. Using a new syngeneic model of bone metastasis (r3T), we...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Natasha, Tajneen, Kuhn, Misty, Kelly, Owen, Rittling, Susan R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606503/
https://ncbi.nlm.nih.gov/pubmed/16436669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050480
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