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Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.

Osteopetrosis is a bone modeling disorder resulting in excessive accumulation of bone matrix due to defective function of osteoclasts, the cells that resorb bone. Mice carrying a targeted disruption of the gene Src that encodes pp60c-src (Src), a nonreceptor protein tyrosine kinase, develop this phe...

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Bibliografische gegevens
Hoofdauteurs: Lowe, C, Yoneda, T, Boyce, B F, Chen, H, Mundy, G R, Soriano, P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1993
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC46536/
https://ncbi.nlm.nih.gov/pubmed/7685105
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