Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.

Osteopetrosis is a bone modeling disorder resulting in excessive accumulation of bone matrix due to defective function of osteoclasts, the cells that resorb bone. Mice carrying a targeted disruption of the gene Src that encodes pp60c-src (Src), a nonreceptor protein tyrosine kinase, develop this phe...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Lowe, C, Yoneda, T, Boyce, B F, Chen, H, Mundy, G R, Soriano, P
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1993
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7685105/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4485
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