Elastin Calcification in the Rat Subdermal Model Is Accompanied by Up-Regulation of Degradative and Osteogenic Cellular Responses

Calcification of vascular elastin occurs in patients with arteriosclerosis, renal failure, diabetes, and vascular graft implants. We hypothesized that pathological elastin calcification is related to degenerative and osteogenic mechanisms. To test this hypothesis, the temporal expression of genes an...

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Hlavní autoři: Lee, Jeoung Soo, Basalyga, Dina M., Simionescu, Agneta, Isenburg, Jason C., Simionescu, Dan T., Vyavahare, Narendra R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2006
Témata:
Original Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606489/
https://ncbi.nlm.nih.gov/pubmed/16436663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050338
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