Elastin Degradation and Calcification in an Abdominal Aorta Injury Model: Role of Matrix Metalloproteinases

BACKGROUND: Elastin calcification is a widespread feature of vascular pathology, and circumstantial evidence exists for a correlation between elastin degradation and calcification. We hypothesized that matrix metalloproteinase (MMP)–mediated vascular remodeling plays a significant role in elastin ca...

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Autores principales: Basalyga, Dina M., Simionescu, Dan T., Xiong, Wanfen, Timothy Baxter, B., Starcher, Barry C., Vyavahare, Narendra R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262646/
https://ncbi.nlm.nih.gov/pubmed/15545515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.CIR.0000148367.08413.E9
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