Elastin Calcification in the Rat Subdermal Model Is Accompanied by Up-Regulation of Degradative and Osteogenic Cellular Responses

Calcification of vascular elastin occurs in patients with arteriosclerosis, renal failure, diabetes, and vascular graft implants. We hypothesized that pathological elastin calcification is related to degenerative and osteogenic mechanisms. To test this hypothesis, the temporal expression of genes an...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Jeoung Soo, Basalyga, Dina M., Simionescu, Agneta, Isenburg, Jason C., Simionescu, Dan T., Vyavahare, Narendra R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2006
Schlagworte:
Original Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606489/
https://ncbi.nlm.nih.gov/pubmed/16436663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050338
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