Absence of Proteinase-Activated Receptor-1 Signaling Affords Protection from Bleomycin-Induced Lung Inflammation and Fibrosis

Activation of the coagulation cascade is commonly observed in the lungs of patients with both acute and chronic inflammatory and fibrotic lung disorders, as well as in animal models of these disorders. The aim of this study was to examine the contribution of the major thrombin receptor, proteinase-a...

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Bibliografiske detaljer
Main Authors: Howell, David C.J., Johns, Robin H., Lasky, Joseph A., Shan, Bin, Scotton, Chris J., Laurent, Geoffrey J., Chambers, Rachel C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2005
Fag:
Original Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606391/
https://ncbi.nlm.nih.gov/pubmed/15855637
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