Proliferation of Estrogen Receptor-α-Positive Mammary Epithelial Cells Is Restrained by Transforming Growth Factor-β1 in Adult Mice

Transforming growth factor (TGF)-β1 is a potent inhibitor of mammary epithelial proliferation. In human breast, estrogen receptor (ER)-α cells rarely co-localize with markers of proliferation, but their increased frequency correlates with breast cancer risk. To determine whether TGF-β1 is necessary...

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Main Authors: Ewan, Kenneth B.R., Oketch-Rabah, Hellen A., Ravani, Shraddha A., Shyamala, G., Moses, Harold L., Barcellos-Hoff, Mary Helen
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2005
Teme:
Original Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1603552/
https://ncbi.nlm.nih.gov/pubmed/16049327
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