Mammary Adipose Tissue-derived Lysophospholipids Promote Estrogen Receptor-negative Mammary Epithelial Cell Proliferation

Lysophosphatidic acid (LPA), acting in an autocrine or paracrine fashion through G protein-coupled receptors, has been implicated in many physiological and pathological processes including cancer. LPA is converted to lysophosphatidylcholine (LPC) by the secreted phospholipase, autotaxin (ATX). Altho...

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Bibliographic Details
Published in:Cancer Prev Res (Phila)
Main Authors: Volden, Paul A., Skor, Maxwell N., Johnson, Marianna B., Singh, Puneet, Patel, Feenalie N., McClintock, Martha K., Brady, Matthew J., Conzen, Suzanne D.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854771/
https://ncbi.nlm.nih.gov/pubmed/26862086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-15-0107
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