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Inhibitors of Cytochrome P450 4A Suppress Angiogenic Responses

Cytochrome P450 enzymes of the 4A family (CYP4A) convert arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE) in blood vessels of several vascular beds. The present study examined the effects of inhibiting the formation of 20-HETE with N-hydroxy-N′-(4-butyl-2-methylphenol) formamidine (HET0...

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Detalhes bibliográficos
Main Authors: Chen, Ping, Guo, Meng, Wygle, Dana, Edwards, Paul A., Falck, John R., Roman, Richard J., Scicli, A. Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602331/
https://ncbi.nlm.nih.gov/pubmed/15681843
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