Complex Genetic Architecture Revealed by Analysis of High-Density Lipoprotein Cholesterol in Chromosome Substitution Strains and F(2) Crosses

Intercrosses between inbred lines provide a traditional approach to analysis of polygenic inheritance in model organisms. Chromosome substitution strains (CSSs) have been developed as an alternative to accelerate the pace of gene identification in quantitative trait mapping. We compared a classical...

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Main Authors: Stylianou, Ioannis M., Tsaih, Shirng-Wern, DiPetrillo, Keith, Ishimori, Naoki, Li, Renhua, Paigen, Beverly, Churchill, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2006 by the Genetics Society of America 2006
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Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602087/
https://ncbi.nlm.nih.gov/pubmed/16951076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.059717
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