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Zebrafish Genomic Instability Mutants and Cancer Susceptibility
Somatic loss of tumor suppressor gene function comprising the second hit of Knudson's two-hit hypothesis is important in human cancer. A genetic screen was performed in zebrafish (Danio rerio) to find mutations that cause genomic instability (gin), as scored by Streisinger's mosaic-eye ass...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Copyright © 2006 by the Genetics Society of America
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1602069/ https://ncbi.nlm.nih.gov/pubmed/16888336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.059386 |
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