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Zebrafish Genomic Instability Mutants and Cancer Susceptibility

Somatic loss of tumor suppressor gene function comprising the second hit of Knudson's two-hit hypothesis is important in human cancer. A genetic screen was performed in zebrafish (Danio rerio) to find mutations that cause genomic instability (gin), as scored by Streisinger's mosaic-eye ass...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Moore, Jessica L., Rush, Lindsay M., Breneman, Carol, Mohideen, Manzoor-Ali P. K., Cheng, Keith C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Copyright © 2006 by the Genetics Society of America 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602069/
https://ncbi.nlm.nih.gov/pubmed/16888336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.059386
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