A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility

A major goal of cancer research has been to identify genes that contribute to cancer formation. The similar pathology between zebrafish and human tumors, as well as the past success of large-scale genetic screens in uncovering human disease genes, makes zebrafish an ideal system in which to find suc...

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Autori principali: Shepard, Jennifer L., Amatruda, James F., Stern, Howard M., Subramanian, Aravind, Finkelstein, David, Ziai, James, Finley, K. Rose, Pfaff, Kathleen L., Hersey, Candace, Zhou, Yi, Barut, Bruce, Freedman, Matthew, Lee, Charles, Spitsbergen, Jan, Neuberg, Donna, Weber, Gerhard, Golub, Todd R., Glickman, Jonathan N., Kutok, Jeffery L., Aster, Jon C., Zon, Leonard I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1198999/
https://ncbi.nlm.nih.gov/pubmed/16150706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506583102
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