p53-Induced Apoptosis Occurs in the Absence of p14(ARF) in Malignant Pleural Mesothelioma

Malignant pleural mesotheliomas (MPMs) are usually wild type for the p53 gene but contain homozygous deletions in the INK4A locus that encodes p14(ARF), an inhibitor of p53-MDM2 interaction. Previous findings suggest that lack of p14(ARF) expression and the presence of SV40 large T antigen (L-Tag) r...

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Hlavní autoři: Hopkins-Donaldson, Sally, Belyanskaya, Larisa L, Simões-Wüst, Ana Paula, Sigrist, Brigitte, Kurtz, Stefanie, Zangemeister-Wittke, Uwe, Stahel, Rolf
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2006
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1601933/
https://ncbi.nlm.nih.gov/pubmed/16867217
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