Dominant negative down-regulation of endotoxin-induced tumor necrosis factor α production by Lps(d)/Ran

We recently showed that adenoviral transfer and expression of the Lps(d)/Ran gene isolated from endotoxin-resistant C3H/HeJ mice could protect endotoxin-sensitive mice from endotoxic shock. Elevation of proinflammatory cytokines, such as tumor necrosis factor α (TNF-α), is thought to be essential fo...

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Autors principals: Yuan, Quan, Zhao, Fangping, Chung, Siu-Wah, Fan, Peidong, Sultzer, Barnet M., Kan, Y. W., Wong, Peter M. C.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC16019/
https://ncbi.nlm.nih.gov/pubmed/10706609
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