Dominant negative down-regulation of endotoxin-induced tumor necrosis factor α production by Lps(d)/Ran

We recently showed that adenoviral transfer and expression of the Lps(d)/Ran gene isolated from endotoxin-resistant C3H/HeJ mice could protect endotoxin-sensitive mice from endotoxic shock. Elevation of proinflammatory cytokines, such as tumor necrosis factor α (TNF-α), is thought to be essential fo...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Yuan, Quan, Zhao, Fangping, Chung, Siu-Wah, Fan, Peidong, Sultzer, Barnet M., Kan, Y. W., Wong, Peter M. C.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2000
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10706609/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.040567797
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