Dominant negative down-regulation of endotoxin-induced tumor necrosis factor α production by Lps(d)/Ran
We recently showed that adenoviral transfer and expression of the Lps(d)/Ran gene isolated from endotoxin-resistant C3H/HeJ mice could protect endotoxin-sensitive mice from endotoxic shock. Elevation of proinflammatory cytokines, such as tumor necrosis factor α (TNF-α), is thought to be essential fo...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10706609/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.040567797 |
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