ICI 182,780-Regulated Gene Expression in DU145 Prostate Cancer Cells Is Mediated by Estrogen Receptor-β/NFκB Crosstalk

Estrogen receptor (ER)-β is the predominant ER subtype in prostate cancer (PCa). We previously demonstrated that ICI 182,780 (ICI), but not estrogens, exerted dose-dependent growth inhibition on DU145 PCa cells by an ER-β-mediated pathway. Transcriptional profiling detected a greater than three-fold...

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Bibliographic Details
Main Authors: Leung, Yuet-Kin, Gao, Ying, Lau, Kin-Mang, Zhang, Xiang, Ho, Shuk-Mei
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1600682/
https://ncbi.nlm.nih.gov/pubmed/16756716
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