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Activation of the human estrogen receptor by the antiestrogens ICI 182,780 and tamoxifen in yeast genetic systems: Implications for their mechanism of action

The antiestrogens tamoxifen and ICI 182,780 have been portrayed as competitive antagonists of the estrogen binding site of the α-form of the human estrogen receptor (ER). However, in functional studies, neither compound has consistently been able to block estradiol-induced transcription. In this rep...

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מידע ביבליוגרפי
Main Authors: Dudley, Mark W., Sheeler, Cameron Q., Wang, Hong, Khan, Sohaib
פורמט: Artigo
שפה:Inglês
יצא לאור: The National Academy of Sciences 2000
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC16302/
https://ncbi.nlm.nih.gov/pubmed/10725345
תגים: הוספת תג
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