Lens opacification by antioestrogens: tamoxifen vs ICI 182,780.

The antioestrogen, tamoxifen, blocks volume-regulated chloride channels and reduces transparency in bovine lenses maintained in vitro. In contrast to tamoxifen, the steroidal antioestrogen, ICI 182780, did not block volume-regulated chloride currents in three cultured cell lines and required 10 fold...

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Bibliographic Details
Main Authors: Zhang, J. J., Jacob, T. J., Hardy, S. P., Higgins, C. F., Valverde, M. A.
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908879/
https://ncbi.nlm.nih.gov/pubmed/8564190
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