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The von Hippel–Lindau tumor suppressor gene product represses oncogenic β-catenin signaling in renal carcinoma cells

Loss of von Hippel–Lindau (VHL) tumor suppressor gene function occurs in familial and most sporadic clear cell renal cell carcinoma (RCC), resulting in the aberrant expression of genes that control cell proliferation, invasion, and angiogenesis. The molecular mechanisms by which VHL loss leads to tu...

詳細記述

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書誌詳細
主要な著者: Peruzzi, Benedetta, Athauda, Gagani, Bottaro, Donald P.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599994/
https://ncbi.nlm.nih.gov/pubmed/16983094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606850103
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