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Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer

Androgen independence is responsible for most prostate cancer lethality, yet currently there are no effective clinical treatments. We have been investigating the mechanisms underlying androgen-independent prostate cancer in Nkx3.1;Pten mutant mice, which display salient features of the disease, incl...

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Hlavní autoři: Gao, Hui, Ouyang, Xuesong, Banach-Petrosky, Whitney A., Gerald, William L., Shen, Michael M., Abate-Shen, Cory
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599986/
https://ncbi.nlm.nih.gov/pubmed/16973750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606836103
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