Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis

Mouse models have provided significant insights into the molecular mechanisms of tumor suppressor gene function. Here we use mouse models of prostate carcinogenesis to demonstrate that the Nkx3.1 homeobox gene undergoes epigenetic inactivation through loss of protein expression. Loss of function of...

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Detaylı Bibliyografya
Asıl Yazarlar: Kim, Minjung J., Cardiff, Robert D., Desai, Nishita, Banach-Petrosky, Whitney A., Parsons, Ramon, Shen, Michael M., Abate-Shen, Cory
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2002
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC122442/
https://ncbi.nlm.nih.gov/pubmed/11854455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042688999
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