Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis

Mouse models have provided significant insights into the molecular mechanisms of tumor suppressor gene function. Here we use mouse models of prostate carcinogenesis to demonstrate that the Nkx3.1 homeobox gene undergoes epigenetic inactivation through loss of protein expression. Loss of function of...

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Detalles Bibliográficos
Main Authors: Kim, Minjung J., Cardiff, Robert D., Desai, Nishita, Banach-Petrosky, Whitney A., Parsons, Ramon, Shen, Michael M., Abate-Shen, Cory
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC122442/
https://ncbi.nlm.nih.gov/pubmed/11854455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042688999
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