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Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis
Mouse models have provided significant insights into the molecular mechanisms of tumor suppressor gene function. Here we use mouse models of prostate carcinogenesis to demonstrate that the Nkx3.1 homeobox gene undergoes epigenetic inactivation through loss of protein expression. Loss of function of...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122442/ https://ncbi.nlm.nih.gov/pubmed/11854455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042688999 |
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