A critical role for p27(kip1) gene dosage in a mouse model of prostate carcinogenesis

In human prostate cancer, the frequent down-regulation of p27(kip1) protein expression is correlated with poor clinical outcome, yet p27(kip1) rarely undergoes mutational inactivation. Here, we investigate the consequences of reducing or eliminating p27(kip1) function for prostate carcinogenesis in...

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Detaylı Bibliyografya
Asıl Yazarlar: Gao, Hui, Ouyang, Xuesong, Banach-Petrosky, Whitney, Borowsky, Alexander D., Lin, Yong, Kim, Minjung, Lee, Hansol, Shih, Weichung-Joseph, Cardiff, Robert D., Shen, Michael M., Abate-Shen, Cory
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2004
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC535400/
https://ncbi.nlm.nih.gov/pubmed/15569926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407693101
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