HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

A unique cohort of HIV-1-infected long term nonprogressors (LTNP) with normal CD4(+) T cell counts and <50 copies/ml of plasma were prospectively recruited for study. HLA typing revealed a dramatic association between the HLA B*5701 class I allele and nonprogressive infection [85% (11 of 13) vs. 9.5...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Migueles, Stephen A., Sabbaghian, M. Shirin, Shupert, W. Lesley, Bettinotti, Maria P., Marincola, Francesco M., Martino, Lisa, Hallahan, Clair W., Selig, Sara M., Schwartz, David, Sullivan, John, Connors, Mark
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15994/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10694578/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050567397
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