Resistance to Replication of Human Immunodeficiency Virus Challenge in SCID-Hu Mice Engrafted with Peripheral Blood Mononuclear Cells of Nonprogressors Is Mediated by CD8(+) T Cells and Associated with a Proliferative Response to p24 Antigen

High levels of resistance to challenge with human immunodeficiency virus type 1 SF162 were observed in animals engrafted with peripheral blood mononuclear cells of four long-term nonprogressors (LTNPs). Resistance was abrogated by depletion of CD8(+) T cells in vivo and was observed only in LTNPs wi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: de Quiros, Juan Carlos Lopez Bernaldo, Shupert, W. Lesley, McNeil, Andrew C., Gea-Banacloche, Juan C., Flanigan, Mark, Savage, Ann, Martino, Lisa, Weiskopf, Emma E., Imamichi, Hiromi, Zhang, Yi-Ming, Adelsburger, Joseph, Stevens, Randy, Murphy, Philip M., Zimmerman, Peter A., Hallahan, Claire W., Davey, Richard T., Connors, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC111681/
https://ncbi.nlm.nih.gov/pubmed/10644376
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi