HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

A unique cohort of HIV-1-infected long term nonprogressors (LTNP) with normal CD4(+) T cell counts and <50 copies/ml of plasma were prospectively recruited for study. HLA typing revealed a dramatic association between the HLA B*5701 class I allele and nonprogressive infection [85% (11 of 13) vs....

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Detalhes bibliográficos
Main Authors: Migueles, Stephen A., Sabbaghian, M. Shirin, Shupert, W. Lesley, Bettinotti, Maria P., Marincola, Francesco M., Martino, Lisa, Hallahan, Clair W., Selig, Sara M., Schwartz, David, Sullivan, John, Connors, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15994/
https://ncbi.nlm.nih.gov/pubmed/10694578
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