Dendritic cells purified from myeloma are primed with tumor-specific antigen (idiotype) and activate CD4(+) T cells
Multiple myelomas produce tumor-specific antigen (TSA) in the form of idiotype (Id) on monoclonal Ig. CD4(+) T cells can recognize Id-peptide on MHC class II molecules and protect against challenges with MOPC315 cells, which are, as common for myelomas, class II-negative. The present study explains...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2000
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10706628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050579897 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|