Dendritic cells purified from myeloma are primed with tumor-specific antigen (idiotype) and activate CD4(+) T cells
Multiple myelomas produce tumor-specific antigen (TSA) in the form of idiotype (Id) on monoclonal Ig. CD4(+) T cells can recognize Id-peptide on MHC class II molecules and protect against challenges with MOPC315 cells, which are, as common for myelomas, class II-negative. The present study explains...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10706628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050579897 |
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