Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex

Two brefeldin A (BFA)-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors, 200-kDa BIG1 and 190-kDa BIG2, were copurified from bovine brain cytosol associated with >670-kDa macromolecular complexes. When observed by immunofluorescence in HeLa S3 and HepG2 cells, endogenous...

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Hauptverfasser: Yamaji, Ryoichi, Adamik, Ronald, Takeda, Kazuyo, Togawa, Akira, Pacheco-Rodriguez, Gustavo, Ferrans, Victor J., Moss, Joel, Vaughan, Martha
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15969/
https://ncbi.nlm.nih.gov/pubmed/10716990
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