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Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex

Two brefeldin A (BFA)-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors, 200-kDa BIG1 and 190-kDa BIG2, were copurified from bovine brain cytosol associated with >670-kDa macromolecular complexes. When observed by immunofluorescence in HeLa S3 and HepG2 cells, endogenous BI...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Yamaji, Ryoichi, Adamik, Ronald, Takeda, Kazuyo, Togawa, Akira, Pacheco-Rodriguez, Gustavo, Ferrans, Victor J., Moss, Joel, Vaughan, Martha
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15969/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716990/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.6.2567
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