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A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics
Novel chemotherapeutics with marked and selective antitumor activity are essential to develop, particularly those that can overcome resistance to established therapies. Iron (Fe) is critical for cell-cycle progression and DNA synthesis and potentially represents a novel molecular target for the desi...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1595448/ https://ncbi.nlm.nih.gov/pubmed/17003122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604979103 |
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