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Selecting protein targets for structural genomics of Pyrobaculum aerophilum: Validating automated fold assignment methods by using binary hypothesis testing

Three-dimensional protein folds were assigned to all ORFs of the recently sequenced genome of the hyperthermophilic archaeon Pyrobaculum aerophilum. Binary hypothesis testing was used to estimate a confidence level for each assignment. A separate test was conducted to assign a probability for whethe...

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Autors principals: Mallick, Parag, Goodwill, Kenneth E., Fitz-Gibbon, Sorel, Miller, Jeffrey H., Eisenberg, David
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC15949/
https://ncbi.nlm.nih.gov/pubmed/10706641
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