Selecting protein targets for structural genomics of Pyrobaculum aerophilum: Validating automated fold assignment methods by using binary hypothesis testing

Three-dimensional protein folds were assigned to all ORFs of the recently sequenced genome of the hyperthermophilic archaeon Pyrobaculum aerophilum. Binary hypothesis testing was used to estimate a confidence level for each assignment. A separate test was conducted to assign a probability for whethe...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Mallick, Parag, Goodwill, Kenneth E., Fitz-Gibbon, Sorel, Miller, Jeffrey H., Eisenberg, David
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15949/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10706641/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050589297
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