Selecting protein targets for structural genomics of Pyrobaculum aerophilum: Validating automated fold assignment methods by using binary hypothesis testing

Three-dimensional protein folds were assigned to all ORFs of the recently sequenced genome of the hyperthermophilic archaeon Pyrobaculum aerophilum. Binary hypothesis testing was used to estimate a confidence level for each assignment. A separate test was conducted to assign a probability for whethe...

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Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριοι συγγραφείς:	Mallick, Parag, Goodwill, Kenneth E., Fitz-Gibbon, Sorel, Miller, Jeffrey H., Eisenberg, David
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 2000
Θέματα:	Biological Sciences
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15949/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10706641/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050589297
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