The Contribution of PspC to Pneumococcal Virulence Varies between Strains and Is Accomplished by Both Complement Evasion and Complement-Independent Mechanisms

Pneumococcal surface protein C (PspC) is a virulence factor of Streptococcus pneumoniae previously shown to play a role in bacterial adherence, invasion, and evasion of complement. We investigated the role of this protein in our murine models of pneumococcal pneumonia with different pneumococcal str...

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Detalhes bibliográficos
Main Authors: Kerr, Alison R., Paterson, Gavin K., McCluskey, Jackie, Iannelli, Francesco, Oggioni, Marco R., Pozzi, Gianni, Mitchell, Tim J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594871/
https://ncbi.nlm.nih.gov/pubmed/16926426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00543-06
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